Gadd45a Activation Protects Melanoma Cells from Ultraviolet B-Induced Apoptosis
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چکیده
منابع مشابه
Autologous nitric oxide protects mouse and human keratinocytes from ultraviolet B radiation-induced apoptosis.
Nitric oxide (NO) can either prevent or promote apoptosis, depending on cell type. In the present study, we tested the hypothesis that NO suppresses ultraviolet B radiation (UVB)-induced keratinocyte apoptosis both in vitro and in vivo. Irradiation with UVB or addition of the NO synthase (NOS) inhibitor N(G)-nitro-l-arginine methyl ester (l-NAME) increased apoptosis in the human keratinocyte ce...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2008
ISSN: 0022-202X
DOI: 10.1038/sj.jid.5700963